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Chatelain, E. Chagas disease drug discovery: toward a new era.
The preparations quickened today as the countdown proceeded smoothly for the space shuttle Discovery toward its planned liftoff at 8 47 A.M. Tuesday.
These investigators each receive a five year appointment and funding to carry out non-conventional scientific exploration and to invent new tools to accelerate the pace of discovery toward curing, preventing and managing every disease.
In the book's preface, Goodwin writes, "It is my greatest hope that the story that follows will guide readers through their own process of discovery toward a better understanding of what it takes to summon the public to demand the action necessary to bringing our country closer to its ancient ideals".
After the impressive successes in drug discovery toward the end of the last century, productivity in the pharmaceutical industry has declined as expenses have gone up.
Over the past 15 years, there has been a noticeable shift in these industries away from drug discovery toward drug development and commercial manufacturing.
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The Center for Neuroscience and Regeneration Research is a state-of-the-art facility dedicated to molecular and cell-based discoveries toward restoration and preservation of nervous system function.
Michael Welsh led the team that made key discoveries toward elucidating the role of the product of this gene, the CFTR protein, as the chemical transporter that allows chloride to move in and out of cells, showing how mutations in the gene and its product cause cells to malfunction and fuel disease development.
He has been mum on the details, but in talking to him over the years, I suspect that it will describe the need to move more aggressively with validating genetic markers and other crucial elements of personalized medicine, while calling for a broad plan to move research and applications of medical discoveries toward a more individualized approach based on a person's own genetics and physiology.
Some decried the lack of scientists of color or female scientists on our list just four women made the top 50, for example—and noted that our search strategy, which started with a handful of Twitter celebrity scientists and looked at who they followed, likely biased our discoveries toward white males.
Translational research helps move basic science and clinical laboratory discoveries toward application in health and medicine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com