Sentence examples for discovery target from inspiring English sources

Examples of the uses of ANNs in target discovery, target validation, and hit evaluation are given.

MK2 kinase is a promising drug discovery target for the treatment of inflammatory diseases.

In addressing a new drug discovery target, the generation of tractable protein substrates for functional and structural analyses can represent a significant hurdle.

Cell membrane receptor-ligand docking is an important initiator of signal transduction and a discovery target for new bone-enhancing drugs.

To validate DAPK as a potential drug discovery target for acute brain injury, the first small molecule DAPK inhibitor was synthesized and tested in vivo.

These findings and experiments with TRPA1 knockout mice suggest that this receptor is an attractive drug discovery target to reduce pain (Chen et al. 2012; Koivisto et al. 2014).

MicroRNAs (MiRNAs) have been regarded as clinically important biomarkers and drug discovery targets.

Antiapoptotic Bcl-2-family proteins Bcl-2 and Bcl-XL have been recently validated as drug discovery targets for cancer.

These non-peptide scaffolds may provide a new platform for future rational drug design and discovery targeting the immunoproteasome.

Herein, we survey the latest developments of in silico approaches to advance epigenetic drug and probe discovery targeting DNMTs.

Faced with a wealth of antibacterial drug discovery targets as a result of bacterial genomics, we need to carefully select which ones to work with.