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Lines 4 10 of the algorithm describe the discovery step of workflow motifs.
During the system discovery step, the mobile terminals equipped with multiple interfaces have to determine which networks can be used and the services available in each network.
This method delivered a high-affinity ligand for a target protein in a single discovery step.
For PhyloGibbs we use the same PWMs for all species because each PWM was built from all species during the PhyloGibbs motif discovery step.
The genome-wide repetitive fragments were also masked for the pattern discovery step using UCSC Genome Browser RepeatMasker annotation (http://www.repeatmasker.org).org
To take the existence of such heterotypic motif clusters into account in our dataset of 166 enhancers, we added a pattern discovery step to identify a shared context between all regions targeted by the same TF, always excluding the left-out test region (Figure 1).
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Ultimately, such models may predict screening outcomes of novel compounds, guiding future discovery steps.
Computer-assisted pathfinding has the potential to save biochemists time in the initial discovery steps of metabolic engineering.
Given appropriately designed chemical libraries [14], HTS campaigns are usually successful by generating lead compounds and knowledge structure activity relationships (SAR)—to facilitate subsequent discovery steps.
The design framework structures the many different and challenging design problems (e.g., solvent selection, reactor design, and design of separation and purification operations), driving the user from the initial drug discovery steps – where process knowledge is very limited – toward the detailed design and analysis.
However, as shown in previous and related work, a more impartial and systematic approach to modeling facial morphology is available and can facilitate both the gene discovery steps, as we recently showed, and DNA-based facial composite construction, as we show here.
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