It is notable that the fusion discovery sensitivities for FusionMap, FusionHunter, deFuse, TopHat-fusion, and ChimeraScan, previously observed in the Edgren_set, are also kept in the Berger_set, and TopHat-fusion is again the best tool in sensitivity after ChimeraScan.
The area under the receiver operating characteristic curve is 0.954 for the four-miRNA signature in the discovery stage (sensitivity = 0.917 and specificity = 0.896) and 0.928 in the validation stage (sensitivity = 0.921 and specificity = 0.934).
While the identity and specific role of these guidance systems awaits discovery, the sensitivity of the CNS axon scaffold to Abl over-expression will be an important tool for identifying these competing pathways.
Mass spectrometric detection is gradually replacing ultraviolet (UV) as the method of choice in bioanalysis, especially in the area of early drug discovery where high sensitivity and rapid sample throughput is required and where samples are frequently pooled or "cocktailed" prior to dosing or analysis.
Two indices may be used to assess the performance of the OxyGene platform: the specificity (improvements in original annotations, see above) and the sensitivity (discovery of missed features).
In the discovery cohort, the sensitivity, specificity and area under the curve (AUC) of the three mRNAs for BE diagnosis were 92 100%, 94 95%, and 0.96 0.97, respectively.
Furthermore, in combination with short-insert fragment libraries and AB/SOLiD sequencing, these arrays provide high target-enrichment rates with relatively even coverage, which was found to be instrumental for reliable heterozygous mutation discovery with high sensitivity and specificity [ 27, 28].
Pawitan et al. [16] assumed that genes are independent and have equal variance, and the paper reports on false discovery rates and sensitivities.
This minimum score is the cutoff used for the computation of false-discovery rate and sensitivity of the search for each TCDB entry (see methods).
Although human brain research has often drawn inspiration from results in nonhuman primate research, this is a 2-way street; the discovery of flow field sensitivity in human V6 will likely stimulate other laboratories to test for flow field sensitivity in macaque V6 using stimuli similar to those described here.
