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The constant decline in drug discovery productivity despite the continuous growth in R&D investments has been on the table for many years and is driving changes in the current business model.
However, we believe that the biggest impact on drug discovery productivity would accrue from achieving two clear objectives: an estimate of human in vivo activity on every compound synthesised and a reliable prioritisation, based on predictions of human in vivo activity, for the next round of synthesis.
In that regard, the Monte Carlo simulation suggests that attempting to improve drug discovery productivity by simply increasing the size of existing working groups may not necessarily be the best solution.
The development of such forms of thought in a society fuels discovery, productivity, and innovation, which in turn, drive economic and social development. .
There are numerous areas of drug discovery in which academically contextualized groups can provide a pre-competitive harbour for the development and testing of new targets, methods and paradigms that can be implemented one day to improve drug discovery productivity.
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It has been assumed that a batch of genetically identical yeast will secrete such drugs at uniform rates, but MIT chemical engineers have made the surprising discovery that drug productivity varies greatly among individual yeast cells.
Medical research inside Biosphere 2 included the effects on humans of lowered oxygen: the discovery that human productivity can be maintained with good health with lowered atmospheric oxygen levels could lead to major economies on the design of space stations and planetary/lunar settlements.
This update, built-in response to user feedback, is focused on improving search, productivity, discovery and sharing.
Khanna, I. Drug discovery in pharmaceutical industry: productivity challenges and trends.
The Library needs to improve and add more access, productivity, and discovery tools for both on- and off-campus research.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com