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Fig. 1 Current drug discovery paradigm in antibiotics.
In-silico methods are an integral part of modern drug discovery paradigm.
But no one has come up with a universal Discovery paradigm for the mainstream audience.
The current drug discovery paradigm allocates a short period of time (3 12 months) for the process of lead identification.
Prodrug interventions should be considered early in the drug discovery paradigm rather than as a technique of last resort.
The wealth of RNA structural data generated by these structures has allowed computational chemists to employ a drug discovery paradigm focused on RNA-based targets.
Similar(38)
Here, we describe disease gene discovery paradigms as applied to SLI families and review the progress this field has made.
In contrast to this view, we argue that cloud computing environments require challenging traditional information paradigms and taking into account social and technological evolutions that dominant current work practices to elaborate adequate knowledge discovery paradigms.
It offers some insights on how the establishment of highly robust proteomics pipelines can be used for studying novel areas such as computational epigenetics, high performance functional studies and new discovery paradigms for drug targets and biomarkers.
Importantly, this approach is adaptable for use in a Chemistry, Manufacture and Control drug screening protocol and may have applications in identifying lineage specific reagents, thus providing additional evidence for the utility of stem cells in screening and discovery paradigms.
Our results also suggest that such a strategy is rich in the potential of identifying lineage specific reagents and provides additional evidence for the utility of stem cells in screening and discovery paradigms.
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Justyna Jupowicz-Kozak
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