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However, the most exciting and novel discovery of the current study is that the intronic portion of the conserved human genome has been subjected to almost exactly the same degree of selective pressure as the exonic component.
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An important discovery in the current study is that high concentrations of ATP can induce SC death in vitro.
One distinct feature of the current study is our discovery that germline L1 and Alu insertions significantly perturb expression of genes relevant to HCC.
Another limitation of the current study is that a small number (n = 54) of cases overlapped in both discovery samples.
39 As by the time of the GWAS publication in December 2012 5 both the discovery and replication genotypes of the current study were completed, PTPN22 and TNIP1 were not included in the current study as candidate genes.
Both the discovery and replication genotypes of the current study were completed by the time of the EOMG GWAS publication in December 2012, 5 hence, the candidate gene selection was not influenced by the GWAS results.
The objective of the current study was to discover and validate SNPs in flax using a combined NGS of RRLs and GBS strategy with the updated annotation based genome-wide SNP discovery pipeline (AGSNP) [ 34, 61].
The current study was initiated by the discovery of a potential novel syndrome at The Children's Hospital of Philadelphia in 2009.
The major discovery of our current study is the link between Sema3-Nrp signaling and PDE4D activity which eventually affects the intracellular cAMP level.
Current study is focused on biomarker discovery on ischemic stroke without any comparison with hemorrhagic stroke.
The aim of our current study was to perform large-scale SNP discovery from gene coding regions of blackcurrant using 2GS 454 pyrosequencing.
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