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The advancement in gene therapy relies upon the discovery of safe and efficient delivery agents and methods.
The design strategy adopted could find potential application in discovery of safe drugs in other therapy areas too.
The future of gene therapy in humans, however, is contingent upon the discovery of safe and effective carriers of genetic material.
If double stranded DNA is proven to be the ultimate target of genomic drug action, intercalation will emerge as a cornerstone of the future discovery of safe and effective pharmaceuticals.
This has led to the discovery of safe systems that prevent sun-induced degradation of potent UVA filters and to the development of new UVA filters with a high photostability.
The discovery of safe and effective antiviral agents from plant extracts may secure humanity from the drug resistant viruses.
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In this review we outline recent progress towards the discovery of safer opioid analgesics.
Not only do these crystal structures contribute unprecedented molecular details of opioid ligand binding and specificity, but they also represent important tools for structure-based approaches to guide the discovery of safer and more efficient opioid therapeutics.
Accordingly, quantifying the accumulation and concentration of polymyxin within tubular cells is very important for the development of novel strategies to ameliorate polymyxin-induced nephrotoxicity, as well as for the discovery of safer, new-generation polymyxins.
These approaches will hopefully facilitate the discovery of safer, more efficacious anticancer drugs that exploit vulnerabilities that are unique to cancer cells by virtue of the mutations they have accrued during tumor progression.
Mr. Freeh said then that the agency was "very pleased at the progress of the investigation," especially with the early breakthroughs made by the Yemenis, including the discovery of two safe houses said to have been used by the bombers and the arrest of a first group of suspects, including a carpenter and welder who reportedly worked with the bombers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com