Advances in the ability to quantitate differences between samples and to detect for an array of post-translational modifications allow for the discovery of classes of protein biomarkers that were previously unassailable.
This field was given great impetus by the discovery of a class of plant hormones known as auxins, which affect cell elongation.
U.S. structure of boranes economics Friedman, Milton U.S. consumption analysis, monetary theory, and economic stabilization literature Bellow, Saul U.S. novelist peace Corrigan, Mairéad Northern Ireland peace Williams, Betty Northern Ireland physics Richter, Burton U.S. discovery of new class of elementary particles (psi, or J) physics Ting, Samuel C.C.
The original Wolff's vascular theory of migraine was supported by the discovery of a class of drugs, the triptans, developed as a selective cephalic vasoconstrictor agents.
The design of novel antiplatelet agents using pyridoxine as a template has led to the discovery of a class of novel cardio- and cerebro-protective agents.
However, the discovery of a class of self-assembling peptides that spontaneously undergo self-organization into well-ordered structures resulted in a conceptual change.
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in many microorganisms but not in humans.
The story of the development of bone morphogenetic protein (BMP) osteoinductive therapy, from the discovery of this class of molecules in 1965 to the publication of randomized clinical trials in 2001 for tibial non-unions and 2002 for spinal fusion, is truly fascinating.
The discovery of a class of small noncoding RNAs, called microRNAs, implies alternative mechanism of regulation of HIF-1α.
However, its structural homology to C. elegans death genes prompted the discovery of a class of proteases now termed caspases [4], [5].
