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In the past year, three landmark clinical trials have shown that a daily dose of the antiretroviral medication Truvada can protect individuals from infection with H.I.V. — a significant discovery, given the failure so far of all efforts to develop a vaccine against the virus.
The bromodomain and extra-terminal (BET) family of epigenetic proteins has attracted considerable attention in drug discovery given its involvement in regulating gene transcription.
It's thrilling to see the Nobel, intended for a "most important discovery," given to a modest, selfless, humanitarian polymath, and perhaps not so much for a stroke of genius as for a lifetime of determination.
Another study found that students active in campus conservative groups avoid coursework in the social sciences — an especially striking discovery given these students' self-evidently strong interest in social and political issues.
The Neanderthal at Spy Cave dined heavily on meat, including the woolly rhinoceros and wild sheep — an unsurprising discovery, given that the bones of woolly rhinoceroses, reindeer, mammoths and horses were found within Spy Cave, and wild sheep lived throughout Europe during that time period, the researchers said.
To maximize the sensitivity of discovery, given limited starting material (145 hearts, ≈20 ìg of protein), identifications were accepted provisionally if they contained at least 1 statistically-validated unique peptide from 1 assigned spectrum.
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Nevertheless, the discovery gave astronomers and alien life-seekers heart.
The discovery gave fresh impetus to the search.
This discovery gave rise to the Babylonian goal-year texts.
The discovery gives doctors a fresh way to target the condition.
The discovery gave me an unexpected sense of connection and responsibility.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com