Sentence examples for discovery effort for from inspiring English sources

Taken together, a small upfront effort in identifying a target-specific [3H] or [125I] radiotracer could lead to significant time and cost saving down the road and could be considered as pre-requisite to initiating any extensive PET discovery effort for a novel CNS target.

This gene discovery effort for O. viverrini should expedite molecular studies of cholangiocarcinogenesis and accelerate research focused on developing new interventions, drugs and vaccines, to control O. viverrini and related flukes.

Together, these papers highlight current status of drug discovery efforts for flavivirus diseases and suggest promising areas for further research.

Our drug discovery efforts for N-type calcium channel blockers in the 4-piperidinylaniline series led to the discovery of an orally active analgesic agent 26.

The combination drugs currently employed are primarily of rational design, but the increased efficacy they provide justifies in vitro discovery efforts for identifying novel multi-target mechanisms.

As a whole, obtaining the active cyclin A without the CDK partner (referred to as monomeric in this work) in a straightforward and facile manner will obviate protein – production issues with the CDK2/cyclin A complex and enable drug discovery efforts for non-ATP competitive CDK inhibition through the cyclin groove.

As described below, a similar focus on peptidomimetic inhibitors has dominated drug discovery efforts for herpesvirus protease inhibitors.

These models were then used to prioritize compounds for acquisition with the aim of enhancing both the speed and diversity of hit-to-lead discovery efforts for mGluR5 positive allosteric modulators (PAMs).

The increased scale of data generation and reduction in associated costs characteristic of second-generation sequencing technologies has recently permitted large-scale single nucleotide polymorphism (SNP) discovery efforts for crop species that previously had limited genomic resources.

35 This receptor is present in the vasculature, the TG and the spinal trigeminal complex of the brainstem and has hence been the subject of drug-discovery efforts for migraine.

While this provides an enviable starting point for PET ligand discovery effort, it also presents a distinctive challenge on how to identify the right leads for PET imaging from such large compound pools.