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Our goal in creating TB Mobile[30] was to make this potentially useful drug discovery data from CDD available in a form accessible to scientists in general and provide a novel way to predict potential targets.
We download this motif discovery data from [ 44].
Second, the Danish discovery data from stage 2 were meta-analysed with the seven replication centres to obtain an overall combined result.
Overall, these results suggest that our method is able to identify CCRTFs with high accuracy by integrating microarray expression data with the motif discovery data from pure in-silico sequence analysis.
Cacao transcriptomes: The Esttik database (http://esttik.cirad.fr/) houses EST discovery data from fifty-six different cDNA libraries constructed from different organs, genotypes and in varying environmental conditions [ 37]. 454 transcriptome: A cDNA library from six mixed tissues of Criollo genotype (B97-61/B2) wasequenceded by Roche/454 technology as previously described [ 36].
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The discovery data were excluded from retraining.
The drug discovery data set derived from the original publication by Cheng et al. contains sites for 24 druggable targets with marketed drugs and three undruggable targets.
The significant SNPs for HTDMYslope and THIslope from the discovery data set were tested in this validation data set.
In a sensitivity analysis, for each GWA investigation, we treated the GWA discovery data as a separate study from the GWA replication data.
We compared the performance of DrugFEATURE to MAPPOD, F-pocket, SiteMap, and DLID using the drug discovery data set, which is derived from Cheng et al.'s original data set.
The aim of this mini-symposium was to present methods of predicting cardiotoxicity (which will be defined throughout this entire manuscript as a synonym of a proarrhythmic effect) from early discovery data.
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