Sentence examples for discovery compounds from inspiring English sources

The search had been prompted by an earlier discovery: compounds that bound to a similar gene receptor were highly effective in treating diabetics, the pharmaceutical industry's most lucrative market.

The 18 Allergan discovery compounds contain a variety of chemical moieties.

Many discovery compounds have low solubility but are potentially valuable as leads.

The second, was a long-term conventional Arrhenius stability experiment (8 weeks in five separate isothermal ovens), conducted in parallel on the same 18 discovery compounds.

A fast gradient HPLC method (cycle time 15 min) has been developed to determine Human Serum Albumin HSAA) binding of discovery compounds using chemically bonded protein stationary phases.

Applying snapshot PK studies to categorize the oral exposure of >1300 discovery compounds as low, moderate or high resulted in an attrition rate of 86%.

The discovery compounded the perplexity and confusion raised by earlier detection of planets beyond the Sun's family, beginning in 1995.

dosing and i.v. infusion to obtain steady-state brain penetration, along with blood clearance, oral exposure and oral bioavailability for each discovery compound, within a 24 hour in-life experiment and only a few (e.g., 3) animals.

The substrates of a transporter are not only useful for inferring function of the transporter, but also important in discovery of compound-compound interactions and reconstruction of metabolic pathways.

Here, we demonstrate a feasible in vivo assay for the discovery of compounds with anti-inflammatory actions from natural compound libraries.

Technology has helped with the early part of the process, the discovery of compounds, but not as much with the costliest and most time-consuming portion of drug development -- clinical trials.