Sentence examples for discovery and quantification from inspiring English sources

The advent of high-throughput genomics has dramatically changed the view of alternative splicing from a single gene perspective to the level of genome-wide discovery and quantification.

The discovery and quantification of genomic variants enables researchers to characterize genomic differences among specific genotypes.

Currently, next-generation sequencing is the platform of choice for the discovery and quantification of miRNAs.

Manual detection is a significant barrier to the discovery and quantification of new factors that influence the filopodia system.

Here, we perform isoform discovery and quantification on transcriptome sequences from before and after zebrafish zygotic genome activation (ZGA).

We review recent developments that have enjoyed a rapid uptake in the discovery and quantification of functional brain architectures.

He brought attention to the fact that in the current status, there is a gap between proteomic biomarker discovery and their quantification.

For example, the ENCODE RNA-seq standards [ 20] suggest that transcriptome profiling of polyadenylated positive samples require modest depths of sequencing, such as 30 million PE reads of length >30 bp, while for novel transcript discovery and strong quantification of known transcript isoforms deeper sequencing is required.

Peripheral blood and derived cell populations are frequently used for biomarker discovery and e.g. quantification of T-cell subpopulation proportions already made its way into clinical routine diagnostics of HIV/AIDS.

Discovery of newly transcribed regions and quantification of known isoforms and novel-transcribed features (NTRs) was performed by Cufflinks v2.0.2 (Trapnell et al. 2010).

The Paragon algorithm in ProteinPilot v.4.2 (AB Sciex, Foster City, CA) was used for protein identification and quantification and false discovery rates (FDRs) assessed by decoy database searching [ 98].