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Although there have been done huge efforts in discovering specific compounds targeting PDK1, nowadays no PDK1 inhibitor has yet entered the clinic.
Accurately discovering specific EGFR mutations, especially uncovering the mutation information from a small amount of mutated cells, which could be covered by the noises from other un-mutated cells, is currently becoming an urgent clinical requirement, since several key mutations have proven playing critical roles influencing drug responses of targeted cancer therapies.
These tasks have been focused on discovering specific rules manually for gene regulation mining from text.
The emergence of mass spectrometry (MS) proteomics technology has brought new opportunities for discovering specific protein markers for early OVCA detection.
Although the prospect of discovering specific multi-targeting drugs is attractive, the actual implementation is a complicated endeavor.
Advances in discovering specific biomarkers for AMD may also provide a very early detection method to direct intervention before development of the disease.
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One effective way to build follower headcount is to use hashtags – words proceeded with a hashtag symbol – which help users to discover specific Instagram posts.
Using a prediction API (Application Program Interface) called Apply Magic Sauce, analysts scour your FB likes and statuses to discover specific personality traits.
Search will also let users filter the library by textbook and author to discover specific study material or information.
Here, we employed structure-based design with a focused chemical library to discover specific MRE11 endo- or exonuclease inhibitors.
Many of these proteins arose out of hit-and-miss efforts to discover specific mutations, fusion partners or chemical modifications that confer desired properties.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com