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Existing pathway analysis techniques are mainly focused on discovering altered pathways between normal and cancer groups and are not suitable for identifying the pathway aberrance that may occur in an individual sample.
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It is sensitive to discover altered glycans as promising markers at glycosylation levels.
The recently discovered altered microRNA expression in schizophrenia [ 4] gave rise to new theories regarding the cause of schizophrenia, highlighting the importance of gene networks [ 5], further supporting the notion that schizophrenia is a multigenic disease.
On the basis of our preliminary work in a trophoblast tissue culture cell line, we discovered altered expression of three human miRNAs and two proteins in placenta from PE patients.
What new evidence was discovered that altered the original findings?
Recently, hundreds of lncRNAs have been discovered, and altered lncRNAs expression has been considered to be correlated with cancer pathogenesis and muscles differentiation [ 29, 30].
Adams was more capable than either of a bipartisan vision; in the brilliant and devoted Abigail, he discovered his alter ego and true political mate.
Plakophilin and desmoplakin mutations have been discovered to alter binding interfaces, structures, and stabilities of folded domains that have been resolved by X-ray crystallography and NMR spectroscopy.
But he has discovered that altering expectations in this idyllic desert paradise isn't easy.
While testing the His-Cre enzyme, we discovered that altering the recombination buffer composition had a marked effect on the number of colonies recovered after transformation of the Cre reaction into bacteria – a step that is traditionally inefficient.
Other studies aimed at discovering cellular processes altered in this myopathy [29] [31] have not proven anymore successful and the molecular aspects of the disease remain obscure yet.
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