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What else but education can turn out the brains that create new science and technology, then use the discoveries to develop more and better jobs?
Many laboratory research scientists view TR as a linear, unidirectional process for using laboratory discoveries to develop therapeutics for study in human clinical trials; however, even this form of TR is iterative, including feedback loops from bedside to bench (15).
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Dr. Karsenty said he was puzzled by the other group's failure to verify his discovery".It is strange, I agree," he said.But if he is correct, he added, the proof will be using his discovery to develop a drug that builds bone.
In this work, we introduce a comprehensive system using enteroviruses 71EV7171) as an example for leading compound discovery to develop new antiviral.
Two studies (11%) by the same research group used pattern discovery to develop temporal models including SAPS II and SOFA data [ 8, 9] (Table 7).
Targeting the pathological mechanism responsible for C9ORF72-associated FTD and ALS is a logical first step in leveraging this discovery to develop new treatments for both C9ORF72-associated disease as well as other forms of FTD and ALS.
Our results also suggest that a computer simulation can be used as a novel discovery tool to develop hypotheses and test mechanistic and therapeutic hypotheses before moving into lengthy and costly clinical trials.
Given the structural similarity of KDMs and the conservation of active site features with multiple homologous enzymes, one of the major challenges for future KDM inhibitor discovery is to develop inhibitors selective for particular (sets of) KDMs.
The aims of drug discovery are to develop: drugs that reduce fracture risk without long-term deleterious effects on the skeleton or other side effects; drugs whose effects cease with cessation of therapy; bone resorption inhibitors that do not inhibit bone formation; anabolic agents; and drugs that are safe, cost-effective, and that act specifically on osteoclasts and/or osteoblasts.
Discovery allows them to develop their own musical skills in a different way, and I'm convinced this does influence the music we make on a number of levels.
My job is to lead the in vivo pharmacology aspect of a drug discovery project and to develop novel technology to facilitate progress.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com