However, the date of the discovery was listed on the announcement as March 7 , 2003 the location of discovery as the Sierra Nevada Observatory, and the name of the discoverer was left blank.
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All the motif sequences and the alterations done to the consensus motif sequences (as discussed in the section on motif discovery) are listed in Table 6.
It should be remembered that in the example of a biomarker search, the protein(s) will be confirmed or dismissed in future targeted validation studies, but failure to identify them in the broad discovery list would preclude them from examination for validation.
Multivariate permutation tests were applied to estimate the proportion of false discoveries in the discovery list.
A complex disease is often characterized with many coordinated molecular changes, which should be considered when evaluating the reproducibility of discovery lists from different studies.
Let O r 12 (or O r 21) represent the number of genes in list 1 (or list 2) which are not shared but significantly positively correlated with at least one gene in list 2 (or list 1), then the POGR scores are calculated as: (3) Both the POG and POGR scores take values ranging from 0 to 1. Usually, a high POG or POGR score is desired for two discovery lists for a disease.
In [11] a scheduling system for grid is introduced which encompasses three phases: resource discovery that lists all the available resources, system selection based on gathered information, and file staging and cleanup done by job execution.
Full names of these genes and those additionally found in the discovery study are listed in Additional file 5.
The detailed structures of the MUC1-based glycopeptides peptide and glycoproteins used in the microarray for screening the discovery set are listed in Table 1, and are based on the glycoforms used to detect reactive autoantibodies in sera from early-stage breast cancer patients (Blixt et al, 2011).
