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To date, no mechanism has been discovered to explain this defect in hypoxic inducibility.
More common low penetrance and/or higher penetrance rare mutations remain to be discovered to explain the missing heritability in sporadic MPN and the missing excess familial risk in MPN.
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T2D-related genetic loci discovered to date explain only a small portion of the T2D heritability.
Another way to envision UMI-Bio is through a short description of an idealized class activity in which a plant cell model is discovered to be inadequate to explain phenomena and an animal cellular model is introduced.
In recent years, a new subset of CD4+ T-cells has been discovered that helped to explain many of the discrepancies in the classic Th1/Th2 model, and it has been termed "Th17" based on its secretion of the novel proinflammatory cytokine IL-17 [ 23].
The same might be said of the itinerant and intrepid author, who candidly admits that she has discovered no neat theory to explain why people fight over religion or why someone like the self-proclaimed Reverend Abdu, a former Muslim Fulani nomad, lives his life as an unpaid proselytizer or why a missionary couple in the Sudan persist although they have not converted a single soul.
One of the founders of string theory -- "the idea that vibrating strings are at the core of electrons, protons and neutrons" -- he is now ardently pursuing Albert Einstein's goal of discovering a single theory to explain "everything".
There's something about suddenly discovering the proper way to explain that one thing that's always been swimming about in the back of your mind in real time.
But the last third of this issue, I discovered, was dedicated to explaining and predicting what New York and the world would be like in the year 2000 — including plenty of fun and beautifully simple charts (now, I'm intrigued!) to help depict specifics of the "future" (now 12 years past): population, oil production, car purchases, even how much meat and wheat we'd eat.
The company said it discovered the problem while trying to explain the mystery of the disappearing bars on its new iPhone 4, a week after some users began complaining that when they held the phone a certain way, the bars indicating signal strength dropped off sharply.
These newly discovered functions of SOCS1 help to explain the increased susceptibility of Socs1 null mice to develop cancer as well as their propensity to develop autoimmune diseases.
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