The Association was clearly aimed at Mary, whom government spies, under the direction of Sir Francis Walsingham, had by this time discovered to be thoroughly implicated in plots against the queen's life.
Evidence has been presented supporting the hypothesis that many proteins that were originally discovered to be required for axon guidance are implicated in the development of the vascular [ 11] and lymphatic systems [ 13].
81 Cav-1 was first implicated in cancer development when it was discovered to be a substrate for v-SRC in Rous sarcoma virus-transformed chicken embryo fibroblasts.
miR-15 and miR-16 are part of a cluster that was among the first to be implicated in cancer, when it was discovered that it is frequently deleted or downregulated in chronic lymphocytic leukemia (CLL) patients [ 94].
However, the pathogenesis of glucose metabolism dysregulation is likely to be much more complex, whereby myriads of pathways are likely to be implicated, and much is still to be discovered and clarified.
"I wanted to be implicated in it.
First to be implicated were cucumbers from Spain.
"Disappointed to be implicated in the #kpgenius account," Bresnan tweeted.
Different approaches are currently available to predict the probability of a newly discovered mutation being implicated in disease.
Future work will address if this newly discovered mechanism is implicated in the activation of specific patterns of gene expression during the development of more complex organisms.
