Sentence examples for discovered targeting from inspiring English sources

This model is fully compatible with the idea that both transcriptional enhancers, the iE/MAR and the 3'E, are involved in SHM, and that high levels of SHM activity require their functional interaction with the yet to be discovered targeting element.

A number of cap-snatching inhibitors discovered targeting the endonuclease site have been reported including 4-substituted 2,4-dioxobutanoic acid derivatives, flutimide (Fig. 5), and N-hydroxamic acid/ N-hydroxyimide.

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Applying these methods to the proximal femurs of osteoporotic women, we discover targeted and apparently synergistic effects of pharmaceutical osteoporosis therapy and habitual mechanical load in enhancing bone thickness.

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Newly discovered targets of Myc repression include a set of microRNA genes, the repression of which contributes to tumor formation.

However, it might be harder to interpret the biological meaning of a discovered target gene, if little or no functional information could be found for it.

Note that drugs whose discovered targets were not annotated in the DrugBank database were used in this study [ 23].

mRNAs with the motif may represent newly discovered targets of mTORC1 dependent translation (Additional file 2: Table S6).

Ongoing clinical trials will shed light on the potential druggability of these interactions, in addition to other newly discovered targets.

Interestingly, the newly discovered targets (bold) and those targets not annotated in the DrugBank (underlined) could also be discovered by the new DRS predictions.