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Such procedure will be carried to avoid false discovered rate due to multiple comparisons.
However, a new sample size was estimated within the same parameters (error of 2.5%, power of 80% and significance of 5%) and including the discovered rate of regular participation in sports, 14.8% (n = 775).
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Sometimes, keep using such intervals could lead to a sharp decrease on single-vehicle discover rate.
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Multiple-comparison adjustment was further applied using Benjamini and Hochberg's false discover rate (FDR) method [19].
The genes, exhibiting ≥2-fold change in expression with the false discover rate (FDR) ≤0.01, were considered as 'differentially expressed' and further examined to identify affected pathways.
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Benjamini and Hochberg's method was used in order to control the false discover rate [41].
Each method produces a regularized t-statistic from which a false discover rate (FDR) can be calculated to identify the most likely DE genes.
The statistical significance (false discover rate (FDR), q-value) and the ratio of the changes in expression was calculated using Significance Analysis of Microarray (SAM) software [14] following LOWESS normalization.
Both the minimum p-value for all tagging SNPs within the gene and minimum false discover rate (FDR) adjusted p-values for the three SNP haplowalk sliding window for VDR and RXRA were significantly associated with RCC risk.
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CEO of Professional Science Editing for Scientists @ prosciediting.com