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Much of what has been learned so far is encouraging, and, as more high-risk genes are discovered, progress can only accelerate.
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Whilst it proved difficult in this chemical series to improve potency against the desired target, a new important insight into the mode of inhibition of TryR by these analogues was discovered, progressing our thinking on how to inhibit effectively this important enzyme.
Fatigue failure by near interfacial crack growth was discovered to progress from the outside edge of the joints towards the center of the package, for all joints.
If I'm right, project management in science needs to allow for the possibility that the investigation might veer in unexpected directions as a result of something discovered in progress.
Oregón's liver disease, they discovered, was progressing much faster than expected.
You do not have to go far into this country to discover that progress still needs to be made.
So far, no one has discovered how to progress without the institutions of government.
At this level you are responsible for completing basic experiments and will be a member of one or more cross-functional "project teams" that focus on discovering and progressing new medicines.
This unusual clinical presentation, most notably incidentally discovered adrenal hyperplasia, progresses gradually throughout the life cycle, and clearly differs from that previously described during primary glucocorticoid resistance associated with other NR3C1 missense mutations.
However, a project team's understanding of the backlog items' business implications and dependencies may often not be deep enough to identify all necessary tasks this early, so in addition to the tasks defined in the beginning of the sprint, more necessary tasks might be discovered as the sprint progresses, making any attempt at progress estimation or risk management difficult.
Once inside, he discovered a meeting in progress.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com