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In this work we validated the discovered networks and analyzed their functionality by expressional profiling in relevant target tissue and by using SNP association data.
The discovered networks were over 20-fold larger and shown to have a significance of P approximately zero, by t-test.
The discovered networks are presented in Figure 1.
We visualize the discovered networks in Figure 1.
36 Figure 1 presents all the discovered networks that we discuss below.
The discovered networks encompass numerous previously known resistance mechanisms which is a strong evidence of the validity of the method.
Similar(52)
Crucifix Lane discovered Network Rail's plan to evict them so they could relocate the other unit because Euan was good friends with the owner of the unit and they spoke about their plan.
Using our method, we have discovered network modules specific to cancer or subtypes of cancers.
We then used the Benjamini-Hochberg [ 51] procedure to correct for multiple testing and eliminate any falsely discovered network connection.
We cannot evaluate the performance of our methodology by comparing the discovered network to the true network for the simple reason that the latter is unknown.
We begin with a random uniform exploration process, and then by modulating the probability of discovering links based on the already discovered network, we study the effect research focus biases can have on the dynamics of the network discovery process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com