And with a PI who was close to retirement and on sabbatical, Fiona discovered difficulty maintaining motivation.
In a recent public controversy Yale University discovered the difficulties of regulating consensual sex.
She quickly became deputy sports editor, and discovered the difficulties and tensions of moving into a male, sporting world.
Having secured election on the basis of a more open and media-conscious conduct of committee affairs, he soon discovered the difficulties of the post.
As you've discovered, weathering difficulties in a relationship draws on specialist skills that can leave the carer feeling washed up and redundant when tranquillity is restored.
Even when potential treatments are discovered, the difficulties involved in accessing the CNS may make surgical intervention to implement such treatment more debilitating, and the presence of the blood brain barrier inhibits therapeutic molecules from passing into the CNS.
While novel siRNA targets are being discovered rapidly, difficulties in siRNA delivery such as anatomical accessibility of the target tissue, slow diffusion and non-specific uptake make achieving a precise degree of protein downregulation nearly impossible.
1. MESS AT MICHIGAN WILL BE HARD TO CLEAN UP Dave Brandon, the new athletic director, discovered the difficulties of navigating the back channels of hiring and firing a football coach.
Downs: The tax credits rebellion and "pig-gate" The prime minister quickly discovered the difficulties of governing with only a small majority when a group of Conservative backbenchers refused to accept his proposals for reducing tax credits, after suggesting in the election that they would be safe from cuts.
In Paris, Bizet discovered the difficulties faced by young and relatively unknown composers trying to get their operas performed.
In 1911, the printing of the second volume was interrupted when Whitehead discovered a difficulty with the symbolism.
