Certainly they brought a change in his work, notably with the introduction of nongeometrical shapes that evoked embryos, plankton, fish and minuscule forms of life that he discovered by using a microscope.
New and improved catalyst compositions were discovered by using a total of seven generations each consisting of 92 potential catalysts.
We have recently reported a new and diverse chemical family of PDE7 inhibitors, the quinazolines ones, discovered by using a ligand-based virtual screening [22].
This putrescine oxidase was discovered by using a plate-based screening method for oxidase activity, which has been used before to screen for improved mutants during directed evolution experiments (Alexeeva et al. 2002).
Lawyers for Ms. Hoang, now 41, argued that IMDB, a popular on-line database covering film and television, had opened the door to age discrimination against her by posting her age, which it discovered by using information she provided as a subscriber.
This approach has the potential to uncover disrupted pathways that cannot be discovered by using overrepresentation and pathways-based methods, which rely on a limited number of annotated genes.
First, peptide pB1 is likely to match a human epitope better because it was discovered by using anti-human ApoB100 antibodies; indeed, our anti-pB1 antibodies reacted stronger with human than with mouse LDL.
To date, all type II inhibitors were discovered by using structure-activity-guided optimization strategies.
A novel class of selective SHP2 allosteric inhibitors was discovered by using the powerful 'SBP'ADMETMET' and 'CDOCKER' techniques.
In this study, a series of novel small molecular CypA inhibitors have been discovered by using structure-based virtual screening in conjunction with chemical synthesis and bioassay.
