Sentence examples for discovered binding from inspiring English sources
We have now identified the CCM1 gene as KRIT1, a recently discovered binding partner of the Krev-1/rap1a tumor suppressor gene (Sahoo et al., in press).
We have now identified the CCM1 gene as KRIT1, a recently discovered binding partner of the Krev-1/rap1a tumor suppressor gene (Sahoo et al., 1999).
Furthermore, after ChIP-chip, enrichment of newly discovered binding regions was quantified similarly by qPCR.
We hypothesized that the microenvironments within known drug-binding sites are likely to recur in newly discovered binding sites.
Although the exact function of this interaction remains to be discovered, binding of MIF to the mutual exclusion element may earmark var loci for mutually exclusive activation.
We sought to use the information derived from the crystal-packing interactions to identify ligands that could span across the phosphopeptide-binding groove into the newly discovered binding site.
Discovering binding sites for TFs and the promoters to which they bind is of prime importance for the understanding of gene regulatory networks they control.
Developing new approaches to both discover binding pockets or "druggable hotspots" and to pharmacologically target these sites with small-molecules will radically expand our scope of the druggable proteome and lead to new disease cures.
While discovering binding motifs of TFs is still important, it can be separated from the learning of transcriptional regulatory networks.
Experimental results establish the principle that dynamic chromatin remodeling data can be used in lieu of gene expression data to discover binding motifs and their transcription factor binding sites.
In the present paper, we describe a strategy to discover binding sites inspired by a technique used for lossy image compression, known as vector quantization [ Nasrabadi and King, 1988], and by analogous methods to identify genes with similar functions and reconstruct phylogenetic trees by clustering algorithms [ Jones and Pevzner, 2004].
