Sentence examples for discovered a pathway from inspiring English sources

Moreover, treating these same Xalkori-resistant cells with an experimental drug designed to block TGF beta-receptors restored sensitivity to Xalkori, though it had no effect on cancer-cell growth on its own.Dr Bernards thinks that in MED12 he has discovered a pathway crucial for the development of drug resistance.

It is now my turn to give my mother a better life, which begun by discovering a pathway to adjust my mother's immigration status.

The C-3 epimerization pathway, the newly discovered A-ring modification pathway is initiated by epimerization of the hydroxyl group at C-3 of the A-ring to form 1α,25(OH 2-3-epi-D3. A ratiOH 2-3-epi-D3OH 2-3-epi-D3sis OH 2-3-epi-D3logs of 1α,25(OH)2D3 is developed based on the knowledge of the various metabolic pathways of 1α,25(OH)2D3.

To address this, we examined SOCE channels farther downstream from receptor activation and discovered a unique pathway association between ET-1 and TRPC3 separate from a more balanced pathway linking B2R activation to both TRPC3 and Orai1.

Scientists have discovered a biochemical pathway that may explain why sunburns and other injuries ache when exposed to heat, says a report in the latest issue of The Proceedings of the National Academy of Sciences.

I found that culturing cardiac valve cells on synthetic hydrogels preserves their normal properties better than the traditional plastic plates do, and I discovered a signaling pathway connecting the stiffness of the supporting scaffold to the cells' cytoskeletal structure.

In the current study, we discovered a signal pathway that is critical for neuron differentiation by hMSCs (Fig 6).

In summary, we discovered a new pathway for biosynthesis of SQ from FPP in bacteria through the concerted actions of the enzymes encoded by hpnC, hpnD, and hpnE.

In summary, we discovered a novel pathway for augmenting exercise performance, which does not involve increased sympathetic tone, but actually reduced AC activity and beta adrenergic receptor signaling, by inhibiting AC5.

Our investigations into the role of the low-efficiency CsManD discovered a novel pathway for the catabolism of l-gulonate in C. salexigens DSM3043 via oxidation or reduction of carbon 5.

Bausch and co-workers discovered a novel pathway for l-idonate metabolism in E. coli K-12 in which l-idonate is converted to d-gluconate via oxidation and subsequent reduction of the C5 hydroxyl group.