Interestingly, through our tests to determine the effectiveness of targeting multiple inhibition sites as a means of combination therapy, we discovered a higher level of system sensitivity to targets in the downstream modules (Raf, MEK and ERK) as opposed to targets in the upstream modules (EGF and Grb2).
Moreover, in a series of patients suffering from colon cancer, Lin et al. [ 54] discovered that a high level of CD133 mRNA in blood predicted disease recurrence.
Many studies in the past two decades have discovered that a high level of research collaboration positively correlates with the quality and quantity of research outcomes [ 1, 2, 4, 17, 26, 27, 29– 31].
Cagnin et al. [ 35] discovered that a high level of PDGF and interleukin was detected in patients with atherosclerosis, suggesting that PDGF could influence the proceeding of atherosclerosis in association with inflammatory factors.
The discovered markers display a high level of specificity for the qPXO79_6 loci and could directly be deployed as foreground markers in marker assisted backcrossing (MABC) schemes.
We discovered that at a high level, all problem-solving processes involve one or both of the following two stages: (1) describing the current understanding of the problem, and (2) describing a desired outcome and working towards a solution.
Boggs and Miller also discovered that "marriage masters" have a high level of selflessness.
They need remedial courses including "core curriculum" courses in science, history, the arts and civics–at the time in their lives when they want to launch out on their own, exploring, discovering and pursuing interests at a high level.
What he discovered was that leaders who had a high level of self-deception were much more likely to be from poorly performing companies and those leaders who demonstrated high levels of self-awareness were associated with high performing companies.
