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Crossing mouse strains harboring different FGFs mutations with FGFRs mutant mouse models is necessary to discover the interactions between FGFs and FGFRs in skeleton development and homeostasis.
For each of the four gene groups (luminal-A gain, luminal-A loss, basal-like gain, and basal-like loss), our goal was to discover the interactions between mRNAs and their regulating miRNAs using their dual expression profiling data under the constraint of the reconstructed breast cancer subtype-trend target information.
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Since more then 1000 different human miRNAs have already been discovered, the interaction between miRNAs and mRNAs is highly complex and currently not completely understood.
Its elements include: (i) coding of collected data into categories, (ii) an iterative process whereby earlier analyses inform further data collection, (iii) the use of a constant comparison technique in the analytic process to discover the conceptual interactions between categories, and (iv) the development of theory that emerges from, and is grounded in, the data [ 21].
We also discover the positive interaction between RUNX1 and YY1 genes.
In order to discover whether the interaction between flexural and dilatational waves in a fluid-filled rectangular duct may be the reason why one observes experimentally a dispersion in the speed of the plane wave inside the duct, a calculation is carried out by the finite element method both in the structure and in the fluid.
In subnetwork I, we discovered the predicted interactions between the miR-17 family and E2F1 for the first time (Additional file 1: Table S6).
In this study we have discovered that the interaction between Lpd and Ena/VASP proteins is positively regulated by c-Abl.
Making good use of emotional design could let the user discover resonance in the interaction between user and product, which could help the product to be more attractive to users.
Systems biology tools as are microarrays can importantly contribute to this knowledge and can also discover novel interactions between the two processes.
Then, the researcher discovers that the interaction between aspirin and the acetylcholinesterase becomes less promising because no interaction between these entities is established in the 3-dimensional subnetwork.
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