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Broad genome sequencing and functional genomics studies, partially motivated by the goal to discover the functions of uncharacterized proteins, have provided a distributed set of data collections suitable to catalyze the inference of the functions of proteins.
It will be of interest, in future studies, to discover the functions of these unusual IgD transcripts.
To discover the functions of the novel transcripts, the Coding Potential Calculator algorithm (http://cpc.cbi.pku.edu.cn/) was used to predict whether they had the ability to encode proteins [ 31, 68].
To discover the functions of all the members, we investigated the transcript level of all genes in eight different tissues and organs as well as under 3 different stress treatments.
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We must discover the function of these genes and their protein products.
Thus, a domain may be a suitable clue to discover the function of proteins.
However, it was the first time to discover the function of miR-148b in metastasis and angiogenesis in HCC.
In this study, we aim to discover the function of miR-26a on glucose metabolism in colorectal cancer cells.
By using the account of representational mechanisms we may discover the function of neural organization and understand why error-correcting pathways exist in the first place.
The work reported in this paper represents another successful example of combining integrative data mining with experimental validation to discover the function of previously uncharacterized or "unknown" proteins.
Using the series of sieves summarized in Fig. 1, we combined comparative genomic and experimental validation approaches to discover the function of 'unknowns'unknowns
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