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Therefore, we aimed to discover the expression patterns that led to different phenotypes.
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Thus, it is not surprising to discover that the expression patterns of miR-1 and miR-133a were similar.
The deep sequencing approach allowed us to discover and analyze the expression pattern of all the small RNAs that would not have been discovered using cloning based approach.
Another aspect of quality is how reliable the expression patterns discovered in libraries really are.
In our study, we discovered the gene expression patterns and ASEs during chondrogenic differentiation of CESCs and analyzed the molecular functions and pathways using bioinformatics tools.
We also propose extensions to deal with missing values, discover anticorrelated and scaled expression patterns, and different ways to compute the errors allowed in the expression patterns.
However, the expression patterns were different.
Transcriptome sequencing offers the possibility to discover novel expression patterns, high abundance transcripts, sequence motifs and splice variants [ 6].
In order to investigate the overall gene regulation and to discover novel expression patterns, all tested cell clones were used for cluster analysis.
These methods make use of available information about the annotations of genes in order to discover gene expression patterns that characterize those annotations.
Therefore, it is important to monitor the expression pattern of genes and to discover the genes that are coexpressed among multiple conditions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com