Sentence examples for discouraging trial from inspiring English sources

Recently, proof of concept was provided by the favourable results of the CAPRISA 004 trial of an antiretroviral-based microbicide [ 19], after many years of discouraging trial outcomes six other potential microbicides and the vaginal diaphragm failed to prevent HIV infection [ 18, 20– 25].

However, discussing such scientific rationales for trials might disrupt the focus of consultations about the child's treatment and therefore discourage trial participation.

The objective was to investigate whether it is justified to discourage trials with less than 80% power.

Though those results were discouraging, the trials could still show a benefit.

While discouraging, these trials have been carried out on unstratified patient groups and there may well be subsets within each disease who are most likely to show improvement during infection.

Wendy Button, a former speechwriter for Mr. Edwards whose reams of notes were central to the prosecution's case, said it was discouraging that the trial had changed nothing.

Although the failure of TNF blockers in heart failure has thus far discouraged further trials in other CVD, evidence to support the hypothesis that TNF blockers are protective against CVD has started to accumulate in RA cohorts.

In this respect, the result of our trial was discouraging.

However, the result of this trial was discouraging.

The results were considered sufficiently discouraging to abandon the trial at this stage on the grounds that there was sufficient evidence in this study that the administration of irradiated autologous cells was of no benefit to patients with high grade astrocytomata.

Early licensing slows the collection of this evidence by discouraging patient recruitment into trials (Rettig, 2007) and by diminishing incentives for other companies to run trials.