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In the second step focus B was then analyzed and a SNV was considered concordant if the SNV was found in at least one read of focus B. Although the SNVs differed substantially between patients, we found no discordant position in any two foci of the same tumor in the three patients at this level of stringency.
Throughout this review we define a reassortant viral lineage of influenza as follows: "a circulating virus or group of viruses in which at least one gene segment of the influenza isolate is located in a discordant position on a phylogenetic tree relative to its other gene segments".
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Crisscross heart is a rare complex congenital malformation (0.1 %) in which there is a spatially discordant positioning of the RA with respect to the LV, and the LA with respect to the RV, although the functional connections are normal [23]].
Subsections Cyathistipulae and Crassicostae present discordant positions between the chloroplast and nuclear phylogenies.
Presence and absence of introns at the discordant positions among the five genomes studied.
Among them, there are seven pairs of introns at orthologous positions and 14 introns at discordant positions.
There is very little (if any) support for the idea of "intron-sliding" as a mechanism to explain discordant positions.
Discordant positions were found more frequent for InDels as opposed to SNVs with 8 (1.17%) loci as false positive and 4 (0.58%) loci as false negative positions.
Discordant positions were determined by complimentary comparisons: SNVs called in preparation A had not to be found in preparation B or vice versa.
More challenging are explanations for the discordant positions of Presbytis and the African genera among colobines in phylogenies revealed by mobile elements and nuclear sequence data.
If this is the case, the exonic regions flanking the extant introns of discordant positions should also have higher GC contents than the exonic sequences flanking conserved introns.
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