Sentence examples for discontinuing the initial from inspiring English sources

Although symptoms improved within 24 hours, the effusion recurred within 48 hours of discontinuing the initial course of ceftriaxone.

The difference remained significant among patients discontinuing the initial TNFi because of inefficacy (−1.7 vs −1.3; p=0.017) but not intolerance (−0.7 vs −0.7; p=0.894).

After the period of randomized intervention, the survivor cohort of the HDS (n = 884) entered a posttrial follow-up to determine whether the risk reductions for microvascular and macrovascular outcomes achieved with tight BP control would be sustained after discontinuing the initial intensive antihypertensive treatment (8).

21 The most common reason for discontinuing the initial injectable therapy was inadequate response (15.3% of the exenatide bid cohort and 6.8% of the insulin cohort); adverse events were the reason for discontinuing initial injectable therapy for 8.2% of the exenatide bid cohort and 0.9% of the insulin cohort.

28 "Persistence", measured in months, was defined as the elapsed time between the index date (which corresponds to the first prescription of study drug) and the ending date (which corresponds to the date of last refill plus the number of pills/tablets prescribed) without discontinuing the initial treatment or without changing to another medication at least 30 days after the initial prescription.

We considered the rate of change in therapy for patients initiated on insulin in the CHOICE study to be relatively high, particularly when compared with similar prospective European observational studies considering treatment change post-insulin initiation, 31, 32 and to be driven primarily by the addition of a new agent rather than discontinuing the initial therapy.

Seventy-seven (8%) of the 997 children discontinued the initial NNRTI (27 NVP, 32 EFV) or protease inhibitor (18) drug for toxicity.

Individuals were identified as "still receiving initial treatment" if they had not switched to or added the other treatment, nor discontinued the initial treatment (experienced a ≥ 15 day gap between outpatient prescriptions, adjusted for early refills).

The combination arm was discontinued after the initial analysis for lack of efficacy; thus, a third of the trial participants were lost [ 12, 38].

Discontinuation because of nausea was only reported with dulaglutide (dulaglutide 1.5 mg: 8 [2.6%]; dulaglutide 0.75 mg: 3 [1.0%]), and the majority of these patients (6) discontinued within the initial 2 weeks of study drug administration.

Eligible for participation in the extension were all subjects from Brazil and the Nordic countries who had participated in the dose-ranging study, had been vaccinated with either the low-dose vaccine or placebo formulations, had not discontinued during the initial 3-year study, and who agreed to participate.