This prompted NASA Astronomy and Physics Director, Jon Morse, to issue a letter on 24 September 2010 to the SIM Lite project manager, informing him that NASA was discontinuing its sponsorship of the SIM Lite mission and directing the project to discontinue Phase B activities immediately or as soon as practical.
As our trial was discontinued at phase II, we were not able to assess the primary survival endpoint of the phase III component.
Development for AD was discontinued after phase I. AAB-003 is Fc-engineered bapineuzumab.
AN1792, an active vaccine, was discontinued in phase II due to meningoencephalitis [ 115] and produced a small increase in CSF Aβ.
However, another vaccine AC-001(A β 1 7 conjugated to inactivated diphtheria toxin) discontinued its phase 2 trial in August 2013, because the studied drug elicited a strong antibody response.
Although acting as a potent LPS antagonist in vitro, Eritoran was recently discontinued in phase III clinical trials because of the lack of statistically significant activity when tested on a panel of 2000 septic patients (Peri & Piazza, 2012).
65, 66 Relacatib was discontinued following a Phase I study that showed possible drug drug interactions with the commonly prescribed medications paracetamol, ibuprofen, and atorvastatin.
Twenty-nine patients completed the study, and two participants in the EA first phase discontinued, one participant because of financial problems and the other participants because of personal problems.
Another survey [ 27] showed that families that prematurely discontinued the first phase of an intensive behavioural treatment program did so because of excessive program length, lack of adequate transportation, unmet expectations, and their child's desire to terminate.
All enrolled analysis set included patients who were enrolled in the study SD standard deviation, WBC white blood cells A total of 503 patients out of 515 discontinued during the treatment phase (including discontinuations due to physician's decision).
