Sentence examples for discontinuation studies from inspiring English sources

Therefore, lithium discontinuation studies may be enriched with patients responding to long-term treatment, in addition to tolerating treatment with lithium.

Discontinuation studies (in which patients who had been in remission on lithium for at least 2 consecutive months were selected, then randomly assigned to continued lithium treatment or placebo/alternative treatment substitution) were excluded from the analyses.

While we excluded lithium discontinuation studies as described above, we included studies enriched for tolerability to lithium (Prien et al. [1973]) or acute response/tolerability to other agents (Calabrese et al. [2003]; Bowden et al. [2003]; Weisler et al. [2011]).

Venlafaxine XR [ 294] and imipramine [ 295] have been shown to prevent relapse in randomized, placebo-controlled, discontinuation studies.

Interestingly, none of the previous controlled dose reduction and discontinuation studies used the appropriate non-inferiority design, included a disease activity guided strategy, or reported cost effectiveness analyses.

In RCT discontinuation studies, mirtazapine [ 748] and clomipramine [ 821] have demonstrated continued improvement compared with placebo over approximately six to 12 months.

In the longitudinal therapy discontinuation study, patients were on low doses of treatment at referral.

To address the issue of missing data associated with early study discontinuation, study endpoint (using LOCF) were also reviewed.

The only clinical trial completed in prostate cancer to date is a randomized Phase II discontinuation study.

One good-quality randomized discontinuation study evaluated abatacept in children with persistent oligoarthritis, extended oligoarthritis, polyarthritis, or systemic JIA [ 6].

In a randomised discontinuation study 88% of patients obtained a clinical benefit from the drug (Bhargava et al, 2009).