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The higher rate of side effects and potentially higher discontinuation rate should also be considered.
(Zyprexa had the lowest discontinuation rate, an efficacy measure).
The discontinuation rate during the 6 months core phase due to AEs was low.
This shift could be associated with a higher discontinuation rate in patients with lower compliance.
The ability to switch to another TNF inhibitor could be a major reason for a high discontinuation rate.
The rosiglitazone discontinuation rate increased following the FDA warning, and currently, rosiglitazone is almost pulled out of the market [31].
Similarly, the INPULSIS trials showed a less than 5% discontinuation rate with nintedanib because of diarrhea [7].
The discontinuation rate due to adverse side effects was between 1 and 3 percent, the company said.
We modeled the PrEP discontinuation rate as distinct from adherence, which was represented within our composite parameter of effectiveness.
The primary endpoint is treatment discontinuation rate.
However, implants had a discontinuation rate of only 5% [ 9].
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