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After discontinuation, monitoring can be continued to ensure that liver function returns to the normal range.
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METHODS:The Life After Stopping TKIs (LAST) study is a large, U.S.-based study that aims to improve the evidence for clinical decision making regarding TKI discontinuation with monitoring in patients with chronic myeloid leukemia who have a deep molecular response to TKI therapy.
42 However, we cannot rule out the possibility of unmeasured factors influencing our calculations, as the accuracy of assessment of discontinuation by monitoring of prescriptions is unknown.
Discontinuation of monitoring immediately before withdrawal of life-sustaining treatment is common practice in our unit in order to give parents time with their child with the least possible interference from medical technology.
Adverse events (AEs) and treatment discontinuations were monitored.
Management of overdose requires discontinuation of eptifibatide, monitoring for bleeding and waiting for clearance (primarily renal).
Conclusions: CFC may support absolute CD4+ T cell count for both guiding HCMV prophylaxis discontinuation and better monitoring HCMV infection in AIDS patients with no previous HCMV disease or having discontinued HCMV prophylaxis.
The apparent loss of kidney function, seen here and in earlier studies [ 10], despite drug discontinuation, would support monitoring potentially more sensitive markers of toxicity such as serum phosphate and FEphos.
Clinical decision support systems (CDSSs) have the potential to improve kidney-related drug prescribing by supporting the appropriate initiation, modification, monitoring, or discontinuation of drug therapy.
This has been important, for example, in informing safe periods for planned discontinuation and for clinical monitoring to prevent relapse.
No patient met protocol-defined clinical laboratory safety monitoring or discontinuation criteria during treatment.
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