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This benefit could be lost, however, by sexual disinhibition and by high PrEP discontinuation, especially with lower PrEP effectiveness (≤50%).
In family planning, discontinuation, especially of oral contraceptives and injectables, is a major reason for unintended pregnancies.
In addition, although the safety profile of recent agents is quite superior in comparison to older medicines, the incidence of side effects, such as sexual dysfunctions, may cause therapy discontinuation, especially in younger patients.
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This design, especially discontinuation of the therapy in nonresponders may decrease the risk of resistance.
Discontinuations hit automakers especially hard, since lines that shut down in some cases were once especially popular.
The most important finding in the study was that Kampo prescriptions led to discontinuation of Western medications, especially opioids.
The link between treatment discontinuation and symptom persistence especially in patients receiving repeated TB treatment over multiple illness episodes is important because it illustrates a subgroup of patients who may benefit from further supportive interventions and who are important candidates for further TB and MDR TB control efforts.
Likewise, discontinuation of HRT can be especially difficult for women on long term HRT or for those who previously had severe climacteric symptoms.
More treatment-related adverse events were reported in patients treated with alprazolam, particularly central nervous system-related AEs, and especially after medication discontinuation.
Thus, the aim of the present research was the study of PT and its enthesis after training and especially following sudden discontinuation of activity.
PTU-induced AAV was defined as follows: (a) the signs and symptoms of vasculitis were temporally related to using PTU, and regressed with its discontinuation; (b) serum ANCA was positive, especially in those with multi-antigenicity; and (c) medical conditions that mimicked vasculitis were excluded, especially infections and malignancies, and other definable types of vasculitis [ 17].
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