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Exact(1)
Any trial that was discontinued was also noted and the reason for discontinuation determined.
Similar(59)
The proportion of patients discontinuing therapy and the time to discontinuation were determined for the anti-TNF and abatacept cohorts.
Discontinuation was determined through confidential linkage with the pharmacy database of the existing province-wide antiretroviral treatment program.
Long-term follow-up continued for 2 years after treatment discontinuation to determine patient-reported progression, initiation of new anticancer treatment, and survival.
Failure was defined as discontinuation of an antiretroviral regimen other than for virologic failure or protocol determined discontinuation.
23 Reasons for discontinuation could not be determined in our study due to the data source used.
24 Physicians' management decisions about continuation or discontinuation of treatment were determined by compiling claims from patients' health records.
22– 25 The Alendronate Phase III Osteoporosis Treatment Study determined that discontinuation of the bisphosphonate alendronate sodium over a 10-year period was associated with gradual loss of clinical effects on bone density and biochemical markers of bone remodeling.
Of the 55 participants with formula-related discontinuation, formula intolerance as determined by the study investigator was the most common reason (Control: 13; LF-0.6: 14; LF-1.0: 15) with fussiness (Control: 5; LF-0.6: 8; LF-1.0: 10) and gas (Control: 6; LF-0.6: 3; LF-1.0: 6) as the most common symptoms.
Kaplan-Meier curve analysis was used to determine discontinuation rates.
The mean interval between diagnostic biopsies and those made to determine discontinuation of treatment was 26.2 ± 6.5 months.
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