Sentence examples for discontinuation before from inspiring English sources

Discontinuation before planned completion of the study implies insufficient efficacy or unacceptable adverse effects.

Table 1 shows the reasons for OnabotulinumtoxinA discontinuation before 24 months.

Fieldworkers contacting participants were then provided with an abridged script to explain basic information about the discontinuation, before advising the participant to visit the clinic for further details.

Given its teratogenicity, childbearing women wait for three years after discontinuation before attempting conception [ 26].

Main outcome measures Trial discontinuation before completion and non-publication after completion.

The absence of an early virologic response was not associated with early treatment discontinuation (before week 12) or dose modification.

Eighteen (5.2%) participants of the 345 in the efficacy population were excluded from the time to median events analysis in the maintenance phase because of discontinuations before the first maintenance-phase visit or lack of evaluable maintenance-phase efficacy data [ 22].

The objective of our study was to quantify changes in AE rates and BMD scores, as well as associated alendronate discontinuation among patients before and after switch from brand to generic alendronate.

The objective of this retrospective chart review was to quantify the number and type of AEs, and the proportion of AEs which led to discontinuation among patients before and after the switch from brand to generic alendronate.

However, the patterns differed significantly by duration of treatment, with higher period-specific discontinuation rates before 24 months in the Medicaid sample and higher period-specific discontinuation rates in the Commercial sample after 24 months.

Although more bosutinib-treated (25%) versus imatinib-treated (9%) patients discontinued treatment because of an AE, the majority of these discontinuations occurred before the 12-month analysis (bosutinib, 19%; imatinib, 6%) (Cortes et al, 2012), consistent with observations with other TKIs for which most AEs occur early during treatment.