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Indeed, the average unit activity presented a clear increase of the discharge probability related to the presence of negative peaks of the LFP (Fig. 2, middle).
Because the type-7 interneurons exhibited nearly identical discharge probability during two unconscious states (slow wave sleep and ketamine-induced anesthesia), it is of special interest to investigate the cellular and molecular identities of the type-7 cells.
Intrinsic hyperexcitability of motoneurons, which increases discharge probability and thereby calcium inflow, has been assumed to participate in the excitotoxic process (Ilieva et al., 2009).
The probability of rejecting the null hypothesis of no differences in hospital discharge probability distributions between two patient groups was evaluated under several scenarios.
Lastly, we evaluated the power for the four methods to reject the null hypothesis of no differences in discharge probability distributions between patient groups, under various scenarios.
When the hazard of mortality is the same between the two patient populations, the power of the methods to reject the null hypothesis of differences in discharge probability distributions are fairly close to each other.
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However, non-linearities and threshold behaviour along the flood risk chain contribute to substantial variability between damage probabilities and corresponding discharge probabilities.
Infection status was not explicitly modeled and, therefore, infected patients had the same infectiousness and discharge probabilities as MRSA carriers.
DOI: http://dx.doi.org/10.7554/eLife.04006.007 10.7554/eLiFigure06.008 Figure 5. Sub-populations of AACs show distinct action potential discharge probabilities during ripples.
Bistrat cells also significantly increased their discharge probabilities during ripples, but their firing frequency was about half of that of the BCs during the ripple events (36 ± 16 Hz, p < 0.01 with respect to BCs, Mann Whitney; Figure 2E).
Apart from in vitro reports (Hajos et al., 2013), to our knowledge, this is the first in vivo evidence of a sub-population of AACs enhancing their discharge probabilities during ripple oscillations, with significant implications for GABAergic regulation of PC discharges during fast network oscillations (see 'Discussion').
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