Figure 2 Proportion of patients with good neurological function at hospital discharge (defined as a Cerebral Performance Category (CPC) 1 or 2) in relation to hypocapnia (PaCO 2 ≤ 30 mmHg), normocapnia (PaCO 2 31 to 49 mmHg), and hypercapnia (PaCO 2 ≥ 50 mmHg) on initial arterial blood gas analysis after initiation of post-ROSC ventilation settings.
Secondary outcome was good neurological function at hospital discharge, defined as a CPC 1 or 2. The CPC is a validated five-point scale of neurological disability and historically the most commonly used outcome measure in post-cardiac arrest research (1: good cerebral performance, 2: moderate cerebral disability, 3: severe cerebral disability, 4: coma/vegetative state, 5: death) [14, 17 19].
In addition, disability/dependency on discharge (defined by a modified Rankin Scale [mRS] score of 3 5) was also included to account for stroke severity on recovery.
The most common signs of abnormal vaginal discharge, defined by the respondents, were odour and excessive amount (35.5% and 24.8% of responses, respectively).
The primary outcome was "successful discharge," defined as discharge following study drug administration, not requiring additional bronchodilators in the ED and not resulting in admission within 72 hours of discharge.
15 Data include hospital and department codes, dates of admission and discharge, surgical procedures performed during the hospital stay, and up to 20 diagnosis codes at discharge, defined according to the International Classification of Diseases, 10th edition (ICD-10) since 1994.
Secondary outcomes included 10-minute ROSC, defined as ROSC within 10 minutes of CPR, and favourable neurological status at hospital discharge, defined as a score of 1 or 2 on the cerebral performance category (CPC) scale [ 20].
QOL aspects were evaluated through the analysis of independence to accomplish daily living activities (IADL) after ICU discharge, defined as the patient's ability to walk, eat by mouth, maintain an oriented conversation and bath himself.
Primary endpoints are morbidity and mortality one month after hospital discharge, defined by the Clavien- Dindo classification of surgical complications (Ann Surg 240(200405–13, 2004) as well as the Comprehensive Complication Index (CCI) (Ann Surg 258(1):1–7, 2013).
The primary endpoint was the number of patients returning to independent functional status at hospital discharge defined as the ability to perform six activities of daily living and the ability to walk independently.
