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Other authors described no discernable increased toxicity, but used athymic NCr-nu ⁄ nu nude mice rather than NSG mice in their xenograft experiments [ 34, 35].
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Pilot GPs in this study did not report large numbers of additional appointments, reflecting the "modest but discernable" increase reported in a previous survey and audit of practices participating in the pilot [ 4].
Channels that receive significantly lower NH3 dose than the stoichiometric one exhibit low NO conversion, whereas there is no discernable increase in the NO conversion above an NH3 dose four times the average.
Thus, administration of IL-21 to chronically SIV infected viremic animals was safe, well tolerated and could augment the cytotoxic potential of T cells and NK cells, promote B cell differentiation with increases in SIV antibody titers without discernable increase in cellular activation.
The most it grows to on average is 8percentt for those parents, and sometimes there's not much a discernable increase.
Co-administration of the GM-CSF genetic adjuvant induced a modest, but discernable increase, in the frequency of HA-specific CD4+ T cells in the lung expressing all three cytokines (4% vs. 1%).
There was no strong evidence for vaccine-specific IFN-γ responses in any of the groups, although there was a small but discernable increase in background response in group C at day 119, four weeks after the last vaccination.
Under basal conditions, when JNK1 was actively pro-apoptotic following JNK2 silencing, there was no discernable increase in JNK1 T183/Y185 phosphorylation (Fig. 2A, compare control lane with JNK2 siRNA lane).
We observed no discernable increase in spores during stationary phase.
It is of note there was no discernable increase or preservation of insulin secretion in child recipients of autologous cord blood infusions after recent-onset type 1 diabetes mellitus [ 25].
In the mammospheres, however, although the level of p53 in the unirradiated cells was higher than in the monolayer population, there was no clearly discernable increase in p53 in response to irradiation with 1 or 10 Gy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com