Sentence examples for discern functional from inspiring English sources

A second limitation is that many algorithms do not provide reliable motif statistics to enable the biologist to discern functional motifs from statistical artifacts.

Functional non-coding RNAs are known to be optimized for good folding energy, although this signal is not strong enough to discern functional from non-functional RNA.

Complementing the computational tools with experimental validation will likely be necessary, especially for large evolutionary distances, to discern functional homology from the superficial similarity of two sequences that share some common inputs (TF binding sites) but distinct outputs.

Recent contributions include analyses of custom genotyping arrays, such as the Immunochip, statistical methods to identify credible sets of causal variants and the addition of functional genomic annotations for coding and non-coding variation to help prioritize variants and discern functional consequence and hence the biological basis of disease risk.

In line with these studies, and in contrast to purely statistical approaches (see e.g. [11], [12]), we pursue the view that discerning functional advantages or disadvantages of topological properties is more reliable if the corresponding dynamical process is taken into account.

Because natural selection preserves functional elements and processes, we know that conservation is an effective method of discerning functional and non-functional cellular processes.

A popular method for discerning functional networks in resting-state functional MRI scans, pICA identified several genetic components that were associated with an AD-relevant structural brain network.

The relative importance of any individual IntFam in these groups is difficult to discern, but functional enrichment provided one approach to identify functions of potential significance (annotated functions for each IntFam of each group are shown in Table S3, and enriched functions for each group are listed in Table S6).

To discern the functional and pharmacological consequences of the supplementary amino acids, different chimerical as well as truncated forms of SRTX were designed and synthesized.

These results also suggest ways in which other neuroendocrine systems can be regulated, and demonstrate how optogenetic tools can discern their functional architecture.

In exploring the smaller clusters holding one- to five-paralogs (656 clusters with a total of 1,724 proteins), it is difficult to discern a functional bias or propose a plausible explanation for paralogy.