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To discern cells with regenerative capacity within the B population, we analyzed expression of the cell surface metalloendopeptidase CD10, which was previously suggested as a potential MaSC marker (Bachelard-Cascales et al., 2010).
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Nor can they provide subcellular spatial information or discern cell-to-cell heterogeneity within the bacterial population.
Furthermore, accurate determination of stage and prognosis requires multiple testing platforms to discern cell types, cell lineage, degree of maturation or point of maturation arrest, and mutational and genetic/molecular status information [ 2, 3].
These isogenic cells (that possess the same genetic background) with differing cell surface glycomes provide a reliable testbed for discerning cell states based on characteristic glycosylation patterns.
Importantly, the nuclear fluorescence of the Tis21-nucGFP and the neurite fluorescence of the Tubb3-mGFP were clearly distinguishable, allowing us to discern between cells that show either only one or both fluorescent cell compartments at the same time (Fig. 3).
Cytokine and blood cell oscillations in PFAPA syndrome are illustrated Figure 5. Future investigations are required to conclusively discern which cells and cytokines are associated with inflammation (fever) in general and which are specific to febrile episodes in PFAPA syndrome.
However, flow cytometry lacks sufficient sensitivity to quantify viral load or discern infected cells from those that have taken up viral antigens.
However, heterogeneous tissue may confound molecular analysis because it is currently impossible to discern which cells contribute which cellular constituents to a given tissue lysate.
SAM demonstrates its ability to discern the cell development and differentiation occurring on the EVPOME devices.
In all the aforementioned studies mice bearing obligatory null alleles were used making it impossible to discern the cell-specific contribution of CYLD to the observed phenotype [8].
In addition, we could discern some cell bodies in the SVZ that were GLAST positive (Fig. 2 A, C ).
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