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The inability, due to strong inter-study clinical heterogeneity (i.e., populations; interventions; outcomes), to combine the results in a formal meta-analysis reduces the effective sample size from which to discern benefits or harm.
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In terms of quality of care, it is difficult to discern the benefits associated with the steep increase in prescriptions, particularly the increase in the number of classes of medications prescribed and the steep increases in the oldest age groups (i.e., 85+).
This shift might have blurred the ability of this trial to discern a benefit of folic acid.
Early on, he wrote in "Dreams From My Father," he discerned the benefits of playing against the '60s stereotype of black militancy.
The ability to discern patient benefit in the absence of patient death or other complications would facilitate both drug development and more appropriate patient care.
In his inner Hell, Satan can rationally discern the benefit of belief even as he can no longer experience it: "never can true reconcilement grow / Where wounds of deadly hate have peirc'd so deep".
Though we did not originally design our study to discern survival benefit for patients, over a median follow up period of 34 months we attained an overall cancer-related survival ratio of 76% (33/43, with two cancer-unrelated deaths), considerably higher than reported.
"It's tough to discern an added benefit from fish oil supplements in that situation," explains Rimm.
The trouble is that these three intermingled organizations are difficult to discern without the benefit of granular management techniques which CEOs must learn to apply.
"In villages where local governments are searching for ways to bolster their economic output, it is difficult to justify preservation of an area if managers and local people cannot discern its tangible benefit".
It's tough to discern who might benefit from all this.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com