Sentence examples for discarded sites from inspiring English sources

Because our crossing scheme produced individuals isogenic for the third chromosome, we discarded sites called as heterozygous as they are likely misaligned reads located in highly repetitive regions.

Given the uncertainty about the samples and due to limited coverage, we discarded sites known to harbor such SNPs based on the 1000 Genomes Project data, to partially circumvent this problem (26, 67).

Since true adaptive mutations are expected to be present in both lineages, we analyzed each lineage separately, discarding sites that are not shared by both human influenza lineages.

Thus, SPALSH is able to overcome some of the limitations of linear multiple-sequence aligners, and specifically it does not discard sites due to varying module grammar, or neutral mutations.

A matched control set of 40,000 random sites was generated in silico on the human genome by discarding sites with the nearest Tsp509I, HpyChIV4, or HinP1 recognition site at <20 bp (the minimum requirement for a blast search) or >500 bp (the maximum estimated length for efficient 454 bead loading).

We consequently decided to conservatively discard sites whose evolutionary rate was above the arbitrary threshold of 2.2 (red line, Fig.2), in the hope of reducing risks of reconstruction artefacts.

To compute CRERs significance, we kept sites with a maximal p-value of 10-4, and imposed a distance of at least six nucleotides between consecutive sites to discard overlapping sites that would bias the computed significance.

Of these, 38 are present in our catalogue; our study discarded 12 sites shown to be representatives of a single lineage, and we were unable to identify two characteristic sites in HA reported by [10].

To ensure sequence quality, we discarded variant sites in the first and last 75 bp of each amplicon segment.

Reads that aligned to multiple reference regions were discarded, and sites containing mismatches were kept only if the coverage was 20X or greater.

To reduce the number of falsely discarded variable sites, for <2% of individuals in the mapping progeny we permitted to have basecalls different from that of the parental lines.