Sentence examples for discard a role from inspiring English sources

She stretched herself in some very big ways, but she knew when to discard a role or try something else".

Nevertheless, this result does not discard a role of ER stress signalling in M. tuberculosis-induced apoptosis, as ER stress-induced cell death can occur in a CHOP-independent way.

Lastly, we have systematically examined the upper large airways and do not discard a role for other cell types such as Clara cells in the maintenance of homeostasis of smaller human airways.

Since astrocytes are organized in networks to regulate plasticity, learning and function of neural circuits [29], [30], we do not discard a possible role in circuit formation inside the mPFC of these new born astrocytes during learning the task.

Therefore, we cannot discard a potential role of those DNA repair genes in which we did not find associations.

To discard a redundant role between PKC isozymes expressed in thymocytes, we used Rottlerin, a compound that specifically inhibits PKC θ activity in T cells when it is used at a low concentration (3  uM).

Nevertheless, these negative results do not discard a possible role of this intron sequences in transcriptional or posttranscriptional processes given the difficulties in carrying out transcriptional comparisons among different genotypes with different flowering behaviour.

Thus, our results do not discard a relevant role of shared CREs in shaping genome architecture, but rather highlight the importance of high-order chromatin coregulatory mechanisms in the OBP gene organization.

Although this could be an indirect effect of the up-regulation of FLC, we cannot discard a more direct role of BRM in the deposition of this mark at FLC chromatin independently of vernalization and, therefore, more related with the EMF2-complex pathway.

Interestingly, the experiments discarding a relevant role of EndoG where performed in caspase-dependent paradigms such as splenocytes [23] and mouse embryonic fibroblasts [24], were caspases and CAD/DFF40 play a major role in DNA degradation.

Mutations in BRM do not affect the vernalization-mediated repression of FLC, discarding a possible role of this protein in such regulation, but a reduction in the amount of H3K27me3 in non-vernalized plants was observed (Figure 3 and 4).